The hemoglobin E syndromes. I. Hemoglobin E in Eti-Turks.

With the technical assistance of Kaniil Tanrikulu H EMOGLOBIN E has been found with variable frequency among peopies of southeast Asia, such as the Thais,’ ’” the Burmese,2 the Malasians,3 the Indonesians,4 ”4’ the Bengalis,5#{176}’5” and Filipinos,6 and Vcddas of Ceylon.T37h Sporadic cases have been encountered in other countries.6’8 In 1955 an example of the hemoglobin E trait was discovered among 131 Eti-Turks.9 In another survey, one instance of sickle-cell-hemoglobin E dlisease and one of hemoglobin E trait were encountered in one family among 155 Eti-Turks.10” An extensive study of the above-mentioned family was therefore carried out in Mersin and Kelahmed, a village in Tarsus. Among 19 members examined, two had sickle-cell-hemoglobin E disease, 11 the hemoglobin E trait, three sickle cell trait, and three were normal. This experience prompted us to determine the incidence of hemoglobin E in Eti-Turks, particularly among the inhabitants of Kelahmecl.